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Sharma Laboratory

Biomaterials and Drug Delivery Systems


Image: cancer and natural killer cells interacting in 3D

Our Research

Sharma Laboratory

Biomaterials and Drug Delivery Systems


Image: PLGA nanoparticles in suspension (via NanoSite, Rinaldi Lab)

Our Research

Sharma Laboratory

Biomaterials and Drug Delivery Systems


Image: photopolymerization of hydrogels by UV light

Our Research

Sharma Laboratory

Biomaterials and Drug Delivery Systems


Image: 3D reconstruction of a healthy knee (nanoCT)

Our Research

Sharma Laboratory

Biomaterials and Drug Delivery Systems


Image: macroporous hydrogel for cell migration and tissue engineering

Our Research

Sharma Laboratory

Biomaterials and Drug Delivery Systems


Image: cross sections of stem cell differentiation into chondrocytes in 3D pellet culture

Our Research

About the Sharma Lab

Our research targets engineering biomaterials capable of presenting biological signals in a site- and/or cell-specific manner within the body. Towards this goal, our team investigates fundamental material-cell interactions to guide the development of targeted drug and cell delivery systems for applications in regenerative medicine and cancer. At the intersection of these two fields are dysfunctional inflammatory mechanisms that propagate tumor development as well as hinder tissue repair/healing.  


Our research focuses include:
  • Investigating the role of specific immune cells and inflammatory mechanisms in tissue injury and pathology
  • Developing biomaterials and targeted drug delivery systems to control inflammatory mechanisms in specific tissues
  • Developing biomaterials and drug delivery systems to improve immunomodulatory cell-based therapies, including stem cell and adoptive immune cell therapies

News in the Sharma Lab

BMES 2023

From October 11-14, 2023, the Biomedical Engineering Society (BMES) held its annual meeting in Seatt…
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BMES 2022

From October 12-15, 2022, the Biomedical Engineering Society (BMES) held its annual meeting in the v…
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BMES 2020!

Although hosted as a virtual event, the Sharma lab was represented by Madison’s work on the on…
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