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Publications

Temples, Madison N., and Blanka Sharma. “Manufacturing of natural killer cells for treating solid malignancies.” Journal of Immunology and Regenerative Medicine (2020): 100031.

Kumar, Shreedevi, and Blanka Sharma. “Leveraging Electrostatic Interactions for Drug Delivery to the Joint.” Bioelectricity (2020).

Temples M, Adjei IM, Djeu J, and Sharma B, Engineered Three-Dimensional Tumor Models to Study Natural Killer Cell Suppression, ACS Biomater. Sci. Eng., May 2020. https://doi.org/10.1021/acsbiomaterials.0c00259 

Brown SB, Wang L, Jungels R and Sharma B, Effects of cartilage-targeting moieties on nanoparticle biodistribution in healthy and osteoarthritic joints. Acta Biomaterialia, 2020. doi: 10.1016/j.actbio.2019.10.003. 

Brown S, Hornyak J, Jungels R, Shah YY, Yarmola EG, Allen KD and Sharma B, Characterization of post‐traumatic osteoarthritis in rats following ACL rupture by non‐invasive knee injury (NIKI), Journal of Orthopaedic Research, 2019 Sep 14. doi: 10.1002/jor.24470. [Epub ahead of print]

Kumar S, Adjei IM, Brown S, Liseth O and Sharma B, Manganese dioxide nanoparticles protect cartilage from inflammation-induced oxidative stress, Biomaterials, 2019 August 31; 224 (119467)

Adjei IM, Jordan J, Tu T, Trinh TL, Wei S, Djeu J, Sharma B, Functional Recovery of NK Cell Activity by Nanoparticle-mediated Delivery of TGFBR2 siRNA, Journal of Interdisciplinary Nanomedicine, 2019. doi: 10.1002/jin2.63

Brown S, Kumar S and Sharma B, Intra-articular targeting of nanomaterials for the treatment of osteoarthritis, July 2019; 93 (239-257)

Adjei IM, Yang H, Plumton G, Maldonado-Camargo L, Dobson J, Rinaldi C, Jiang H and Sharma B, Multifunctional nanoparticles for inracellular drug delivery and photoacoustic imaging of mesenchymal stem cells, Drug Delivery and Translational Research, June 2019; 9(3): 652-666 *featured on journal cover

Adjei I, Temples M, Brown S, Sharma B, “Targeted nanomedicine to treat bone metastasis,” Pharmaceutics, 2018 Oct 25; 10(4): 205.

Martin-Pena A, Plumton G, Porter RM, McCarrell T, Morton A, Ghivizzani SC, Sharma B, Palmer GD,Transcriptional Reporters for in vitro monitoring of chondrogenesis in 3D culture systems, European Cells and Materials, 2018 Oct 12;36:156-170.

Wolf, MT, Zhang, H, Sharma, B, Albers, R, Elisseeff, JH, Phase II trial of ChonDux: a photoreactive chondroitin-sulfate/PEGhydrogel that provides durable repair of full thickness cartilage defects in the knee, Cartilage, 2018 Oct 3: 1- 11 [Epub ahead of print].

Brown S, Pistiner J, Adjei I, Sharma B, Nanoparticle properties for delivery to cartilage: the implications of disease state, synovial fluid, and off-target uptake, Molecular Pharmaceutics, 2019 Feb 4; 16(2): 469-479

Adjei, I, Sharma B, Labhasetwar V, Inhibition of bone loss with surface modified, drug-loaded nanoparticles in an intra osseous model of prostate cancer. Journal of Controlled Release, 2016 Apr 15;232:83-92.

Tonello S, Moore MC, Sharma B, Dobson J, McFetridge P, Controlled release of a heterogeneous human placental matrix from PLGA microparticles to modulate angiogenesis. Drug Delivery and Translational Research, 2016 Apr; 6(2): 174-183.

Sharma B, Varghese S, Progress in Orthopaedic Biomaterials and Drug Delivery. Drug Delivery and Translational Research 2016 Apr;6(2):75-6.

Sridharan B, Sharma B, Detamore MS, A Roadmap to Commercialization of Cartilage Therapy in the United States of America. Tissue Engineering Part B Reviews, 2016 Feb; 22(1): 15-33

Adjei IM, Sharma B, Modulation of tumor microenvironment for cancer treatment: a biomaterials approach. Journal of Functional Biomaterials, 2015 Feb 17;6(1):81-103

Sharma B, Peetla C, Adjei I, Labhasetwar V, Selective biophysical interactions of engineered nanoparticles with cancer cell lipids improves tumor targeting and gene therapy. Cancer Letters, 2013 Jul 1;334(2):228-36.

Sharma B, Fermanian S, Gibson M, Unterman S, Cascio B, Coburn J, Hui AY, Marcus N, Gold GE, Elisseeff JH, Human cartilage repair with a photoreactive adhesive-hydrogel composite, Science Translational Medicine, 2013 Jan 9;5(167):167ra6.

Prabha S, Sharma B, Labhastewar V, Inhibition of Tumor Angiogenesis and Growth by Nanoparticle-mediated p53 Gene Therapy, Cancer Gene Therapy, 2012 Aug;19(8):530-7

Sharma B, Ma W, Panyam J, Adjec I, Dimetrijevic S, Labhasetwar V, Nanoparticle-mediated p53 Gene Delivery for Tumor Inhibition, Drug Delivery and Translational Research, 2011 Feb; 1(1):43-52

Manthe RL, Foy SP, Krishnamurthy N, Sharma B, Labhasetwar V, Tumor Ablation and Nanotechnology, Molecular Pharmaceutics, 2010 Dec 6;7(6):1880-98.

Hillel A, Taube J, Cornish T, Sharma B, Halushka M, McCarthy E, Hutchins G, Elisseeff JH, Characterization of human mesenchymal stem cell engineered cartilage: analysis of ultrastructure, cell density, and chondrocyte phenotype as compared to native adult and fetal cartilage, Cells Tissues Organs, 2010;191(1):12-20.

Cascio BM, Sharma B, The Future of Cartilage Repair, Operative Techniques in Sports Medicine, 2008 Oct; 16(4):221-224

Ramaswamy S, Gurkan I, Sharma B, Fishbein KW, Cascio B, Spencer RG, Assessment of tissue repair in full thickness chondral defects in the rabbit using magnetic resonance imaging transverse relaxation measurements, Journal of Biomedical Materials Research Part B, 2008 Aug;86B(2):375-80.

Hwang NS, Varghese S, Carter A, Theprungsirikul P, Sharma B, Elisseeff JH., Response of Zonal Chondrocytes to Extracellular Matrix Hydrogels, FEBS Letters, 2007 Sep 4;581(22):4172-8.

Wang DA, Varghese S, Sharma B, Strehin I, Fermanian S, Gorham J, Fairbrother DH, Cascio B, Elisseeff JH, Multifunctional chondroitin sulphate for cartilage tissue-biomaterial integration, Nature Materials, 2007 May; 6(5):385-92.

Sharma B, Williams CG, Kim TK, Malik A, Sun DD, Leong KW, Elisseeff JH, Designing Zonal Organization into Tissue Engineered Cartilage, Tissue Engineering, 2007 Feb;13(2):405-14.

Sharma B, Williams CG, Khan MK, Hanson P, Elisseeff JH, In vivo chodrogenesis of mesenchymal stem cells in a photopolymerized hydrogel, Plastic and Reconstructive Surgery, 2007 Jan;119(1):112-20.

Li Q, Wang J, Shahani S, Sun DD, Sharma B, Elisseeff JH, Leong KW, Biodegradable and photocrosslinkable polyphosphoester hydrogel, Biomaterials, 2006 Mar;27(7):1027-34.

Elisseeff J, Puleo C, Yang F, Sharma B, Advances in skeletal tissue engineering with hydrogels. Orthod Craniofac Res, 2005 Aug;8(3):150-61.

Al-Hadlaq A, Elisseeff JH, Hong L, Williams CG, Caplan AI, Sharma B, Kopher RA, Tomkoria S, Lennon DP, Lopez A, Mao JJ, Adult Stem Cell Driven Genesis of Human-Shaped Articular Condyle, Ann Biomed Eng, 2004 July;32(7):911-923.

Sharma B, Elisseeff JH, Engineering structurally organized cartilage and bone tissues. Ann Biomed Eng, 2004 Jan;32(1):148-59.

Wang DA, Williams CG, Li Q, Sharma B, Elisseeff JH, Synthesis and characterization of a novel degradable phosphate-containing hydrogel, Biomaterials, 2003 Oct;24(22):3969-80.

Kim TK, Sharma B, Williams CG, Ruffner MA, Malik A, McFarland EG, Elisseeff JH, Experimental model for cartilage tissue engineering to regenerate the zonal organization of articular cartilage, Osteoarthritis Cartilage, 2003 Sep;11(9):653-64.

Books, Contributors of Chapter(s)

Adjei I, Plumton G, Sharma B, “Oxidative Stress and Biomaterials: The Inflammatory Link” in Oxidative Stress and Biomaterials: The Science, Challenges and Opportunities, Dziubla T and Butterfield D.A., Elsevier, 2016 Jun; 89-115

Adjei I, Sharma B, Labhasetwar V, “Nanoparticles: Cellular uptake and cytotoxicity” in Nanomaterials: Impacts on Cell Biology and Medicine, Capco D and Yongsheng C, Eds, Adv Exp Med Biol. 2014;811:73-91.