Maria Coronel, along with fellow doctoral students Jiapu Liang and Ying Li, recently published our findings on the translation of our oxygen generating material, OxySite, into macroencapsulation devices. This manuscript, published in the journal Biomaterials, evaluates the capacity of OxySite to supplement beta cells within macroencapsulation devices, which are notoriously hypoxic. These findings outline the […]

Nicholas Abuid, along with research assistant scientist Kerim Gattás Asfura, and undergraduate student Emily Schofield recently published our findings on the fabrication of antioxidant layer-by-layer coating for protecting encapsulated cells from free radical damage. This manuscript, published in the journal Advanced Healthcare Materials, evaluates the capacity of cerium oxide nanoparticle layers to protect encapsulated beta […]

Kaiyuan Jiang, along with postdoctoral fellow Deborah Chaimov and graduate students Smit Patel, Jiapu Liang, Sydney Wiggins, and Magda Samojlik,and in collaboration with Dr. Cheslea Simmons’ lab at UF, recently published our findings on the fabrication of decellularized extracellular matrix (ECM) hydrogels for islet culture. This manuscript, published in the journal Biomaterials, evaluates the capacity of […]

Congrats to Drs Weaver, a Stabler lab PhD alumni, as well Dr. Garcia, her current postdoctoral advisor and corresponding author, and the rest of his team, on their recent publication of our collaborative work on examining the impact of vascularization of macroencapsulation platforms. These results will help improve the engraftment of islet transplants that are immunoisolated […]

Dr. Stabler was recently elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows! The College of Fellows is comprised of outstanding bioengineers in academia, industry and government, representing the top 2 % of medical and biological engineering professionals. Stabler was elected for her outstanding contributions in the design of translational bioactive materials for cellular transplantation, […]

Congrats to Drs Buchwald, as well Dr. Tomei and her lab, for the recent publication of our collaborative work on examining the impact of alginate encapsulation of human islets on their dynamic responses to glucose stimulation. This study developed a robust computational model to predict the impact of alginate encapsulation, as well as the size of […]

Anthony Frei, along with graduate students Ying Li, Kaiyuan Jiang, and in collaboration with Dr. Buchwald at UMiami, recently published our findings on the impact of the local release of figolimod, a promising immunomodulatory and pro-angiogenic agent, from macroporous scaffolds on islet survival and function. This manuscript, published in the Journal of Tissue Engineering and […]

It has been a busy month in the Stabler lab, with both Kaiyuan Jiang and Anthony Frei successfully defending their PhD theses! Dr. Jiang defended his dissertation entitled “LOCAL MODIFICATION OF POLYDIMETHYLSILOXANE-BASED SCAFFOLD IMPLANTS TO IMPROVE ISLET GRAFT EFFICACY AND MODULATE HOST RESPONSE”, where he highlighted the important of modulating inflammation within the islet microenvironment. Dr. Frei defended […]

Congrats to Drs Buchwald and Ricordi, as well as lead authors Marta and Alejandro, for the recent publication of our collaborative work on examining the impact of low oxygen and inflammatory signals on the metabolomic profile of human pancreatic islets. This study may help lead to the identification of potential biomarkers and provide another means to track […]