Our latest article is featured on the cover of the February issue of the journal Diabetes.
Cianciaruso C, Phelps EA, Pasquier M, Hamelin R, Demurtas D, Alibashe Ahmed M, Piemonti L, Hirosue S, Swartz MA, De Palma M, Hubbell JA, Baekkeskov S.
Diabetes. 2017 Feb;66(2):460-473. doi: 10.2337/db16-0671.
On the cover: Primary rat islet cells immunostained for insulin (green), the exosome marker CD81 (red), trans Golgi marker TGN38 (magenta), and nuclei (blue) reveal colocalization of insulin and CD81 in a subgroup of insulin-positive vesicles budding off from the trans Golgi membranes. Image courtesy of Chiara Cianciaruso, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. Her article, “Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity,” appears in this issue of Diabetes (p. 460).
Image Credit: Chiara Cianciaruso (EPFL)