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Engineering the Endocrine Pancreas

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Islet Biology and Type 1 Diabetes

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Seeing Inside Beta Cells

in super-resolution detail

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Welcome to the Phelps research group!

Our lab’s mission is to employ an engineering approach to solve significant problems in health and biology.

Our primary focus is the pancreatic islets of Langerhans and their diseases with an emphasis on beta cell dysfunction and autoimmunity in type 1 diabetes.

We specialize in biomaterials technologies as the basis for regenerative strategies and to discover novel biological insights.

Research Overview

Engineered Cellular Microenvironments

Bio-artificial matrices to program cellular responses

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Countering Autoimmunity

Engineering solutions to treat autoimmune disease like T1D

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Immunopathology and Cell Biology of Autoantigens

Understanding the underlying causes and triggers of autoimmunity in T1D

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New Frontiers in Islet Biology

Pushing the boundaries of knowledge on the biology of islet endocrine cells

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Latest News

Kevin Ling Presents at BMES 2019!

Undergraduate Kevin Ling presenting his poster “Sustained GABA Delivery Implants for Beta Cell Regeneration” at the 2019 Biomedical Engineering Society conference in Philadelphia, PA
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New publication on beta cell imaging

The paper titled, “Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation” describes a n…
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