Our lab’s mission is to employ an engineering approach to solve significant problems in health and biology.

Our primary focus is the pancreatic islets of Langerhans and their diseases with an emphasis on beta cell dysfunction and autoimmunity in type 1 diabetes.

We specialize in biomaterials technologies as the basis for regenerative strategies and to discover novel biological insights.

Research Overview

Etiopathology of type 1 diabetes

Understanding the underlying causes and triggers of T1D autoimmunity

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Islet physiology

biosensors to image islet function

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Biomaterials for islet replacement

Bio-artificial matrices to program cellular responses

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Immune tolerance

Engineering solutions to treat autoimmune disease like T1D

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Islet paracrine signaling

How does the community of cells in the islet coordinate their behavior?

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