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Stabler Laboratory – Diabetes Tissue Engineering

Stabler lab publication featured in Science Translational Medicine!

Our recent publication on engineering an “infectious” Treg biomimetic was featured as an Editor’s Choice in Science Translational Medicine. The article, entitled “Contagious Biomaterials” highlights the potential impact of our studies in generating tolerance microenvironments for foreign cell grafts. Congrats to senior author Ethan Yang and the rest of the Stabler […]

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New publication on engineering an “infectious” Treg published in Biomaterials!

Our recent study on engineering an “infectious” Treg via chemoselective conjugation of TGF-beta1 to biomaterial surfaces has been published in the journal Biomaterials.  Congrats to the fantastic team, including lead author Ethan, volunteer med school student Josh, Research Assistant Scientist Kerim, and our fantastic immunology collaborator Allison Bayer! Engineering an “infectious” Treg biomimetic through […]

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Congratulations to Jaime Giraldo for successful completion of his Ph.D!

Congratulations to Jaime Giraldo on successful completion of his Ph.D! His thesis, entitled “PEGylation and Bioactive Modification of Pancreatic Islet Surfaces to Enhance Graft Survival in Cell Therapy for Type I Diabetes”, explored the PEGylation of islets to complement short-course immunotherapy in preclinical models, as well as the conjugation of bioactive […]

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New publication on local drug delivery design published in Tissue Engineering!

Our recent study on designing a biomaterial implant for local drug release using dexamethasone as the model agent has been published in the journal Tissue Engineering.  Congrats to the fantastic collaborative team, including lead author Jessica, Ph.D students Song and Yang, and our DRI collaborators Drs Antonello Pileggi, Camillo Ricordi, and Peter Buchwald! […]

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New $1M grant funded on macroencapsulation

Dr. Stabler, along with her collaborator Dr. Andrés Garcia (Georgia Institute of Technology), were awarded a 3-year grant from the Juvenile Diabetes Research Foundation (JDRF) on their collaborative project entitled “Engineered Bioactive Hydrogel Macrodevices for Islet Transplantation”. This grant, which provides over $1 million in funding, uses bioactive biomaterials capable of protecting cells […]

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Congratulations to Ethan Yang on successful completion of his Ph.D!

Congratulations to Ethan Yang on successful completion of his Ph.D! His thesis, entitled “Development of immunomodulatory biomaterials for the islet transplant niche”, explored the tethering of proteins or nanoparticles to biomaterial coatings for active modulation of innate and adaptive immune responses. Now, he is back to Medical School!  

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New publication on engineering antioxidant biomaterials published in Acta Biomaterialia!

Our recent study on designing a self-renewing antioxidant encapsulating biomaterial using cerium oxide nanoparticles has been published in the journal Acta Biomaterialia. Congrats to the lead author Jessica Weaver! Antioxidant cerium oxide nanoparticle hydrogels for cellular encapsulation by Weaver, JD and Stabler, CL Link to article: here

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New publication on modeling insulin responsiveness within alginate capsules published in Biomed Eng Online!

Our collaboration with Dr. Peter Buchwald’s group on characterizing the effect encapsulation has on the insulin response of pancreatic isletshas been published in the journal Biomed Eng Online.  Congrats to the collaborative team, including lead author Dr. Peter Buchwald and his team, and our student Jessica Weaver! Experimental evaluation and computational […]

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