Publications from the Hudalla Lab 

Wong, K.M., Wang, Y., Seroski, D.T., Hudalla, G.A., Mehta, A.K., Hall, C., & Paravastu, A.K. Molecular Complementarity and Structural Heterogeneity within  Co-assembled Peptide β-Sheet Nanofibers. NanoScale (2020).

Farhadi, S.A., Fettis, M.M., Liu, R., & Hudalla, G.A. Synthetic Tetramer of Galectin-1 and Galectin-3 Amplifies Pro-Apoptotic Signaling by Integrating the Activity of Both Galectins. Frontiers in Chemistry (2020).

Restuccia, A., Seroski, D.T., Kelley, K.L., O’Bryan, C.S., Kurian, J.J., Knox, K.R., Farhadi, S.A., Angelini, T.E., & Hudalla, G.A. Hiearchical Self-Assembly and Emergent Function of Densley Glycosylated Peptide Nanofibers. Communications Chemistry (2019).

Liu, R. & Hudalla, G.A. Using Self-Assembling Peptides to Integrate Biomolecules into Functional Supramolecular Biomaterials. Molecules (2019). 

Fettis, M.M., Farhadi, S.A., & Hudalla, G.A. A Chimeric, Multivalent Assembly of Galectin-1 and Galectin-3 with Enhanced Extracellular Activity. Biomaterials Science (2019).

Farhadi, S.A., Bracho-Sanchez, E.R., Fettis, M.M., Seroski, D.T., Freeman, S.L., Restuccia, A., Keselowsky, B.G., & Hudalla, G.A. Locally Anchoring Enzymes to Tissues via Extracellular Glycan Recognition. Nature Communications (2018) *Featured in Editors’ Highlights*

Restuccia, A., Fettis, M.M., Farhadi, S.A., Molinaro, M., Kane, B., & Hudalla, G.A. Evaluation of self-assembled glycopeptide nanofibers modified with N,N’-diacetyllactosamine for selective galectin-3 recognition and inhibition. ACS Biomaterials Science and Engineering (2018).

Fettis, M.M. & Hudalla, G.A. Engineering Reactive Oxygen Species-Resistant Galectin-1 Dimers with Enhanced Lectin Activity. Bioconjugate Chemistry (2018).

Restuccia, A. & Hudalla, G.A. Tuning carbohydrate density enhances protein binding and inhibition by glycosylated β-sheet peptide nanofibers. Biomaterials Science (2018).*Featured as cover illustration*

Farhadi, S.A., Bracho-Sanchez, E., Freeman, S.L., Keselowsky, B.G., Hudalla, G.A. Enzymes as Immunotherapeutics. Bioconjugate Chemistry (2018).

Seroski, D.T., Restuccia, A., Sorrentino, A.D., Knox, K.R., Hagen, S. J., Hudalla, G.A. Co-Assembly Tags Based on Charge Complementarity (CATCH) for Installing Functional Protein Ligands into Supramolecular Biomaterials. Cellular and Molecular Bioengineering (2016).

Farhadi, S.A. & Hudalla, G.A. Engineering galectin-glycan interactions for immunotherapy and immunomodulation. Experimental Biology and Medicine (2016).

Fettis, M.M., Wei, Y., Restuccia, A., Kurian, J.J., Wallet, S.M., Hudalla, G.A. Microgels with tunable affinity-controlled protein release via desolvation of self-assembled peptide nanofibers. J. Materials Chemistry B (2016).*Featured as Hot Paper*

Restuccia, A., Fettis, M.M., Hudalla, G.A. Glycomaterials for immunomodulation, immunotherapy, and infection prophylaxis. J. Materials Chemistry B (2015).*Featured as cover illustration*

Hudalla, G.A. & Murphy, W.L. Mimicking the Extracellular Matrix: The Intersection of Matrix Biology and Biomaterials. Royal Society of Chemistry Press, London, 2015.

Restuccia, A., Tian, Y.F., Collier, J.H., & Hudalla, G.A. Self-Assembled Glycopeptide Nanofibers as Modulators of Galectin-1 Bioactivity. Cellular and Molecular Bioengineering (2015).

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Past & External Publications

T. Sun, H. Han, G.A. Hudalla, Y. Wen, R.R. Pompano, J.H. Collier. “Thermal stability of self-assembled peptide vaccine materials.” Acta Biomaterials (2016).

G.A. Hudalla, T. Sun, J. Z. Gasiorowski, H. Han, Y.F. Tian, A.S. Chong, and J.H. Collier. “Gradated Assembly of Multiple Proteins into Supramolecular Nanomaterials.” Nature Materials (2014).

Parlato, A. Johnson, G.A. Hudalla, WL Murphy. “Adaptable poly (ethylene glycol) microspheres capable of mixed-mode degradation.” Acta biomaterialia (2013).

G.A. Hudalla, J.A. Modica, Y.F. Tian, J.S. Rudra, A.S. Chong, T. Sun, M. Mrksich, J.H. Collier. “A self-adjuvanting supramolecular vaccine carrying a folded protein antigen.” Advanced Healthcare Materials (2013).

Y.F. Tian, G.A. Hudalla, H. Han, J.H. Collier. “Controllably degradable β-sheet nanofibers and gels from self-assembling depsipeptides.” Biomaterials Science (2013).

G.A. Hudalla, J.T. Koepsel, W.L. Murphy. “Surfaces that sequester serum-borne heparin amplify growth factor activity.” Advanced Materials (2011).

G.A. Hudalla, W.L. Murphy. “Biomaterials that regulate growth activity via bioinspired interactions.” Advanced Functional Materials (2011).

G.A. Hudalla, W.L. Murphy. “Chemically well-defined self-assembled monolayers for cell culture: towards mimicking the natural ECM.” Soft Matter (2011).

G.A. Hudalla, N.A. Kouris, J.T. Koepsel, B.M. Ogle, W.L. Murphy. “Harnessing endogenous growth factor activity modulates stem cell behavior.” Integrative Biology (2011).

G.A. Hudalla, W.L. Murphy. “Immobilization of peptides with distinct biological activities onto stem cell culture substrates using orthogonal chemistries.” Langmuir (2010).

G.A. Hudalla. “Chemically well-defined cell culture substrates to characterize the influence of extracellular factors on mesenchymal stem cell function.” Dissertation abstract (2010).

G.A. Hudalla and W.L. Murphy. “BIOT 15-Well-defined, peptide-presenting SAM substrates for stem cell culture.” ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2009).

G.A. Hudalla and W.L. Murphy. “Noncovalent localization of heparin sulfate proteoglycans enhances bFGF-mediated cell proliferation.” ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2009).

G.A. Hudalla, W.L. Murphy. “Using “click” chemistry to prepare SAM substrates to study stem cell adhesion.” Langmuir (2009).

G.A. Hudalla and W.L. Murphy. “PMSE 438-Using noncovalent interactions to modulate local soluble signaling.” ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2008).

G.A. Hudalla, T.S. Eng, W.L. Murphy. “An approach to modulate degradation and mesenchymal stem cell behavior in poly(ethylene glycol) networks.” Biomacromolecules (2008).


G.A. Hudalla, B.G. Keselowsky, E.R. Bracho-Sanchez, A. Restuccia, M. Fettis, S.A. Farhadi, S. Freeman. “Targeted Effector Proteins and Uses Thereof.” US Patent App #62/478,880 (2017). 

G.A. Hudalla and D.T. Seroski. “Co-Assembly Peptides, Nanostructures, and Methods of Making and Using the Same.” US Patent App #15/672,783 (2017).

J.H. Collier and G.A. Hudalla. “Methods and compositions involving fibrillizing polypeptides for nanofibers.” US Patent 9,200,082 (2015).

W.L. Murphy and G.A. Hudalla. “Spatial control of signal transduction.” US Patent 8,389,009 (2013).

W.L. Murphy, G.A. Hudalla, J. Koepsel, J.S. Lee, S. Levengood. “Proteoglycan-binding peptides that modulate stem cell behavior.” US Patent App. 13/092,548 (2011).


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