Meghan Ferrall-Fairbanks, Ph.D.

Meghan Ferrall-Fairbanks, Ph.D.

1275 Center Drive,
Biomedical Sciences Building,
Gainesville, FL 32610

Assistant Professor

Quantitative systems biology, mathematical modeling, cancer heterogeneity and evolutionary dynamics


B.S., Mechanical Engineering, University of Florida, 2012
Ph.D., Biomedical Engineering, Georgia Institute of Technology & Emory University, 2017



Research Summary:

Dr. Ferrall-Fairbanks’ research focuses on using quantitative biology approaches to cultivate a mechanistic understanding of tumor heterogeneity and evolution to optimize cancer treatment strategies. Ecology and evolutionary forces in cancer allows a tumor to alter its growth and metastasis. The Battling Evolution through Adaptive Therapies (BEAT) Cancer Lab integrates computational, mathematical, and wet-lab experimental techniques to investigate tumor heterogeneity at the molecular, tissue, and systems levels.

Honors and Awards:

  • AACR Doreen J. Putrah Cancer Research Foundation Scholar-in-Training Award, 2020
  • BMES Career Development Award, 2019
  • Junior Scientist Partnership Award, 2018
  • BMES Career Development Award, 2018
  • Georgia Tech Faces of Inclusive Excellence, 2015
  • Tau Beta Pi Fellow, 2013-2014
  • National Science Foundation Graduate Research Fellowship Program Honorable Mention, 2013

Selected Publications:

Google Scholar Citations Link

Miroshnychenko D, Baratchart E, Ferrall-Fairbanks MC, Vander Velde R, Laurie MA, Bui M, Altrock PM, Basanta D, Marusyk A. “Spontaneous cell fusions as a mechanism of parasexual recombination in tumor cell populations.” Nature Eco & Evol (2021). doi: 10.1038/s41559-020-01367-y PMID: 33462489

Damaghi M, West J, Robertson-Tessi M, Liping X, Ferrall-Fairbanks MC, Stewart PA, Persi E, Fridley BL, Altrock PM, Gatenby RA, Sims PA, Anderson ARA, Gillies RJ. “The harsh microenvironment in early breast cancer selects for a Warburg phenotype.” Proceedings of the National Academy of Sciences of the United States of America. 2021 Jan 19; 118(3): e2011342118. doi: 10.1073/pnas.2011342118 PMID: 33452133

Ferrall-Fairbanks MC, Kieslich CA, Platt MO. “Reassessing enzyme kinetics: considering protease-as-substrate interactions in proteolytic networks.” Proceedings of the National Academy of Sciences of the United States of America. 2020 Feb 11; 117(6) 3307-3318. doi: 10.1073/pnas.1912207117 PMID: 31980525

Ferrall-Fairbanks MC, Barry ZT, Affer M, Shuler MA, Moomaw EW, Platt MO. “PACMANS: A Bioinformatically Informed Algorithm to Predict, Design, and Disrupt Protease-on-Protease Hydrolysis.” Protein Science, 2017 Apr; 26(4):880-890. doi: 10.1002/pro.3113 PMID: 28078782

Cvetkovic C*, Ferrall-Fairbanks MC*, Ko E, Grant L, Kong H, Platt MO, Bahir R. “Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines.” (* co-first author) Scientific Reports, 2017 Jun 19; 7(1):3775. doi: 10.1038/s41598-017-03723-8 PMID: 28630410

Ferrall-Fairbanks MC*, West DM*, Douglas SA, Averett RD, Platt MO. “Computational predictions of novel cysteine cathepsins-mediated fibrinogen degradation.” (* co-first author) Protein Science, 2018 Mar; 27(3):714-724. doi: 10.1002/pro.3366 PMID: 29266558

Grant L*, Raman R*, Cvetkovic C, Ferrall-Fairbanks MC, Diaz GP, Hadley P, Platt MO, and Bashir R. “Longterm cryopreservation and revival of tissue engineered skeletal muscle.” (* co-first author) Tissue Engineering Part A. 2019 Jan 9. doi: 10.1089/ten.TEA.2018.0202 PMID: 30412045

Ferrall-Fairbanks MC, Ball M, Padron E, Altrock PM. “Leveraging single cell RNA sequencing experiments to model intra-tumor heterogeneity.” JCO Clinical Cancer Informatics. 2019 Apr: 3:1-10. doi: 10.1200/CCI.1800074 PMID: 30995123

Ferrall-Fairbanks MC, Glazar DJ, Brady RJ, Kimmel GJ, Zahid MU, Altrock PM, Enderling H. “Re: Simulation analysis for tumor radiotherapy based on three-component mathematical models.” Journal of Applied Clinical Medical Physics. 2019 Jul; 20(7)204-205. doi: 10.1002/acm2.12608 PMID: 31145529