Structural and Functional Neuroimaging in Parkinson’s Disease

01/30/2012 - 11:45am to 12:35pm
Dr. David Vaillancourt, Applied Physiology and Kinesiology, Neurology, and Biomedical Engineering, University of Florida

Biomarkers or specific tests to detect Parkinson’s disease (PD) are a pivotal goal to effective diagnosis and to the development of novel therapies.  A potentially influential technique which could serve as a non-invasive biomarker of PD is magnetic resonance imaging.  Our research team has developed non-invasive, multimodal imaging techniques to characterize the structure and function of cortical and subcortical targets in PD.  The purpose of this lecture is to: 1) describe our recent work using diffusion tensor imaging in healthy aging and de novo PD, 2) describe recent studies using functional magnetic resonance imaging in de novo PD, and 3) describe a recent two-year randomized clinical trial on the effects of resistance exercise for patients with PD.

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